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Selected Publications for William Dunphy
- Kumagai, A. and Dunphy, W.G. (1996). Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts. Science 273, 1377-1380.
- Coleman, T.R., Carpenter, P.B., and Dunphy, W.G. (1996). The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts. Cell 87, 53-63.
- Kumagai, A., Yakowec, P.S., and Dunphy, W.G. (1998). 14-3-3 proteins act as negative regulators of the mitotic inducer Cdc25 in Xenopus egg extracts. Mol. Biol. Cell 9, 345-354.
- Patra, D. and Dunphy, W.G. (1998). Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase-promoting complex at mitosis. Genes and Development 12, 2549-2559.
- Kumagai, A., Guo, Z., Emami, K.H., Wang, S.X., and Dunphy, W.G. (1998). The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts. J. Cell Biol. 142, 1559-1569.
- Kumagai, A. and Dunphy, W.G. (1999). Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25. Genes and Development 13, 1067-1072.
- Guo, Z. and Dunphy, W.G. (2000). Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends. Mol. Biol. Cell 11, 1535-1546.
- Kumagai, A. and Dunphy, W.G. (2000). Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol. Cell 6, 839-849.
- Guo, Z., Kumagai, A., Wang, S.X., and Dunphy, W.G. (2000). Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes and Development 14, 2745-2756.
- Lee, J., Kumagai, A., and Dunphy, W.G. (2001). Positive regulation of Wee1 by Chk1 and 14-3-3 proteins. Mol. Biol. Cell 12, 551-563.
