Rothenberg's Home
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Selected Publications for Ellen Rothenberg
- Hernández-Hoyos, G., Anderson, M. K., Wang, C., Rothenberg, E. V., and Alberola-Ila, J. 2003. GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation. Immunity 19, 83-94.
- Warren, L. A. and Rothenberg, E. V. 2003. Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors. Curr. Opin. Immunol. 15, 166-175.
- Yui, M. A., Sharp, L. L., Havran, W. L., and E. V. Rothenberg. 2004. Preferential activation of an Interleukin-2 (IL-2) regulatory sequence transgene in TCRgd and NKT cells: subset-specific differences in IL-2 regulation. J. Immunol. 172, 4691-4699.
- Telfer, J. C., Hedblom, E. E., Anderson, M. K., Laurent, M. N., and Rothenberg, E. V. 2004. Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes. J. Immunol. 172, 4359-4370.
- Anderson, M. K., Pant, R., Miracle, A. L., Sun, X., Luer, C. A., Walsh, C. J., Telfer, J. C., Litman, G. W., and Rothenberg, E. V. 2004. Evolutionary origins of lymphocytes: Ensembles of T-cell and B-cell transcriptional regulators in a cartilaginous fish. J. Immunol. 172, 5851-5860.
- Rothenberg, E. V. and Pant, R. 2004. Origins of lymphocyte developmental programs: Transcription factor evidence. Semin. Immunol. 16, 227-238.
- Yui, M. A. and Rothenberg, E. V. 2004. Deranged early T cell development in immunodeficient strains of non-obese diabetic (NOD) mice. J. Immunol. 173, 5381-5391.
- Rothenberg, E. V. and Taghon, T. 2005. Molecular genetics of T-cell development. Annu. Rev. Immunol. 23, 601-649. PDF
- Dionne, C. J., Tse, K. Y., Weiss, A. H., Franco, C. B., Wiest, D. L., Anderson, M. K., and Rothenberg, E. V. 2005. Subversion of T lineage commitment by PU.1 in a clonal cell line system. Devel. Biol. 280, 448-466.
- Rothenberg, E. V. 2005. Thymic regulation – hidden in plain sight. Science 307 (5711), 858-859.
- Taghon, T., David, E.-S., Zúñiga-Pflücker, J. C., and Rothenberg, E. V. 2005. Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling. Genes Dev. 19, 965-978.
- Adachi, S., and Rothenberg, E. V. 2005. Cell type-specific epigenetic marking of the IL2 gene at a distal cis-regulatory region in competent, nontranscribing T cells. Nucl. Acids Res. 33, 3200-3210. PDF
- Taghon, T., Yui, M. A., Pant, R., Diamond, R. A., and Rothenberg, E. V. 2006. Developmental and molecular characterization of emerging β- and δ-selected pre-T cells in the adult mouse thymus. Immunity 24, 53-64.
- David-Fung, E.-S., Yui, M. A., Morales, M., Wang, H., Taghon, T., Diamond, R. A., and Rothenberg, E. V. 2006. Progression of regulatory gene expression states in fetal and adult pro-T cell development. Immunol. Rev. 209, 212-236.
- Wang, D., Claus, C. L., Vaccarelli, G., Braunstein, M., Schmitt, T. M., Zúñiga-Pflücker, J.-C., Rothenberg, E. V., and Anderson, M. K. 2006. The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors. J. Immunol. 177, 109-119.
- Franco, C. B., Scripture-Adams, D. D., Proekt, I., Taghon, T., Weiss, A. H., Yui, M. A., Adams, S. L., Diamond, R. A., and Rothenberg, E. V. 2006. Notch/Delta signaling constrains re-engineering of pro-T cells by PU.1. Proc. Natl. Acad. Sci. USA 103, 11993-11998.
- Rothenberg, E. V. 2007. Cell lineage regulators in B and T cell development. Nat. Immunol. 8, 441-444.
- Rothenberg, E. V. 2007. Regulatory factors for initial T-lymphocyte lineage specification. Curr. Opin. Hematol. 14, 322-329.
- Tydell, C. C., David-Fung, E.-S., Moore, J. E., Rowen, L., Taghon, T., and Rothenberg, E. V. 2007. Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway. J. Immunol. 179, 421-438.
- Rothenberg, E. V. 2007. Negotiation of the T-lineage fate decision by transcription factor interplay and microenvironmental signals. Immunity 26, 690-702.
- Taghon, T., Yui, M. A., and Rothenberg, E. V. 2007. Mast cell lineage diversion of T lineage precursor cells by the essential T cell transcription factor GATA-3. Nat. Immunol. 8, 845-855.
- Rothenberg, E. V., Moore, J. E., and Yui, M. A. 2008. Launching the T-cell-lineage developmental programme. Nat. Rev. Immunol. 8, 9-21. doi:10.1038/nri2232.




